品名

丙烯酸-2-羟乙酯; 丙烯酸-β-羟乙酯; 乙二醇单丙烯酸酯; 2-Hydroxyethyl acrylate; 2-Hydroxyethyl-2-propenoate; Ethylene glycol monoacrylate; CAS：818-61-1

理化性质

无色液体,有令人愉快香味。分子式C5-H8-O3。分子量116.13。相对密度1.10(25℃)。凝固点-60℃。沸点174.44℃。闪点104.44℃(开杯)。与水混合。可燃。加热分解,放出辛辣烟气。

接触机会

化工中间体。

国内主要生产厂商:北京东方化工厂

侵入途径

主要经呼吸道吸入。

毒理学简介

大鼠经口LD50: 650 uL/kg; 吸入LCLo: 500 ppm/4H。小鼠经口LD50: 601 mg/kg。兔经皮LD50: 1010 uL/kg。

对皮肤有轻微刺激; 对眼有严重刺激。

临床表现

无中毒报告。

美国HSDB引用文献：

*THE TOXICITY OF THE ACRYLATES DECREASES WITH INCREASING MOLECULAR WEIGHT. ... HUMAN SIGNS & SYMPTOMS FOLLOWING INGESTION OF ACRYLIC MONOMERS INCL COLLAPSE, SEVERE RESPIRATORY DIFFICULTIES, & CNS STIMULATION. INHALATION OF HIGHER CONCN MAY CAUSE MARKED IRRITATION, SALIVATION, CONJUNCTIVAL IRRITATION, & PRONOUNCED PULMONARY IRRITATION OR EDEMA. PROLONGED SKIN OR EYE CONTACT MAY RESULT IN SEVERE TISSUE DAMAGE. THE PATHOLOGY FROM SINGLE EXPOSURE IS CONTRARY TO REPEATED EXPOSURE EFFECTS, WHICH INCL PULMONARY CONGESTION OR HEMORRHAGE & CLOUDY SWELLING OF LIVER & KIDNEY. /ACRYLATES/ [R15, 2292]

*LOW MOLECULAR WEIGHT OXYGENATED ACRYLATES SUCH AS 2-HYDROXYETHYL ACRYLATE ... EXHIBIT PHYSIOLOGICAL PROPERTIES SIMILAR TO THOSE OF ETHYL ACRYLATE ... UPON HYDROLYSIS, TOXICITY OF THE ACID APPEARS DOMINANT OVER THAT OF THE ALCOHOL. [R15, 2297]

处理

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