品名

三硫化锑; 三硫化二锑; 硫化亚锑; 锑橙; 锑朱; Antimony Trisulfide; Antimony glance; Antimony orange; Stibnite; CAS：1345-04-6

理化性质

灰色有光泽结晶块、黑灰色粉末、红色变体、黑色斜方晶体。分子式Sb2S3。分子量339.72。相对密度4.12。熔点550℃。沸点约1150℃。不溶于水; 溶于浓盐酸、硫化铵和硫化钠溶液。在盐酸中产生硫化氢,并生成三氯化锑。遇明火或与强氧化剂接触由于自发化学反应而着火。与氯酸盐、过氯酸、三氧化二铊接触由于自发化学反应而爆炸。加热分解或与酸或酸烟接触生成硫氧化物和锑; 与水或水蒸气反应产生有毒和可燃蒸气。

接触机会

用于颜料、玻璃、火柴、炸药、烟火等的生产。在生产与使用过程中易接触。

国内主要生产厂商:湖南冷水滩市锡矿山

侵入途径

消化道与呼吸道。

毒理学简介

大鼠腹腔注射LDLo: 1390mg/kg。小鼠腹腔注射LD50: 209mg/kg。

参见<锑及其化合物>。

临床表现

参见<锑及其化合物>与<三氯化锑>。

美国HSDB引用文献：

*Chronic poisoning from handling antimony sulfide /from mining/ in Morocco has been reported. Symptoms ... /included/ headache, muscular pains, vertigo, anorexia, and altered blood makeup. [R17, 1514]

*Workmen in a plant where antimony trisulfide was used in the manufacture of grinding wheels were studied. This study focused on cardiovascular status, since prior to the study there had been six sudden deaths in a group of 125 workers exposed to antimony for 8 months to 2 years. The deaths were suspected to be due to heart disease. In the workers studied, 14 of 113 had blood pressures that were >140/90 mm Hg, and 37 of 75 showed significant changes in their EKGs, mostly the T-wave. Ulcers were detected in 7 of 111 exposed persons (63 per 1,000) as compared with 15 per 1,000 in the total plant population. No other disorders suspected of being related to antimony exposure were observed. Although use of antimony trisulfide was discontinued, EKG changes persisted in 12 of 665 workers subsequently reexamined. [R18]

*SYMPTOMATOLOGY: A. SUBACUTE POISONING 1. IRRITANT ACTIONS. EYES: PAINFUL CONJUNCTIVITIS, PHOTOPHOBIA, LACRIMATION, & CORNEAL OPACITY. RESP TRACT: RHINITIS WITH ANOSMIA, TRACHEOBRONCHITIS ... PULMONARY EDEMA WITH DYSPNEA, SOMETIMES LATE BRONCHOPNEUMONIA. SKIN: DIRECT CONTACT (AS SOLN) MAY PRODUCE ERYTHEMA & PAIN. /SULFIDE/ [R19,p. III-201]

*SYMPTOMATOLOGY: A. SUBACUTE ... 2. GI EFFECTS: PROFUSE SALIVATION, NAUSEA, VOMITING, DIARRHEA. 3. CENTRAL NERVOUS EFFECTS: GIDDINESS, HEADACHE, VERTIGO, AMNESIA, CONFUSION ... UNCONSCIOUSNESS. 4. MISCELLANEOUS: TACHYPNEA, PALPITATIONS, TACHYCARDIA, ARRHYTHMIA, SWEATING, WEAKNESS, & MUSCLE CRAMPS. /SULFIDE/ [R19,p. III-201]

*SYMPTOMATOLOGY: B. ACUTE POISONING: 1. SUDDEN COLLAPSE & UNCONSCIOUSNESS ... 2. DEATH FROM PROMPT RESP PARALYSIS, USUALLY WITH TERMINAL ASPHYXIAL CONVULSION. 3. AFTER SUBLETHAL EXPOSURES RECOVERY ... SLOW ... RESIDUAL COUGH, CARDIAC DILATATION, SLOW PULSE, PERIPHERAL /SRP- NEUROPATHY/, ALBUMINURIA ... AMNESIA OR ... PSYCHIC DISTURBANCE. /SULFIDE/ [R19,p. III-201]

处理

参见<锑及其化合物>。

标准

车间空气卫生标准：中国MAC锑及其化合物1.0 mg/m^3(以Sb计); 美国ACGIH TLV-TWA锑化合物0.5 mg/m^3（以Sb计）

危规：GB6.1 类61506。

本内容搜集自互联网，版权归原作者所有