氯溴甲烷_MSDS化学品安全技术说明书

氯溴甲烷-MSDS化学品安全技术说明书

发表时间：2011-10-31浏览次数：评论：分享：顶：踩：

品名

氯溴甲烷; 氯溴亚甲基; Bromochloromethane; CAS：74-97-5

理化性质

无色透明液体、气味似氯仿。分子式C-H2-Br-Cl。分子量129.38。相对密度1.930(25/25℃)。凝固点-88℃。沸点67.8℃。蒸气密度4.46。蒸气压20.66～21.33 KPa(155～160mmHg25℃)。不溶于水; 能与四氯化碳、三氯甲烷、甲醇混溶。物质本身不燃或燃烧困难。加热分解，产生氯化氢、溴化氢、光气、一氧化碳、溴。不能与化学性质活泼金属,如钙、铝粉、锌、镁共存。

接触机会

可作为灭火剂,有时用作化学合成的中间体。

侵入途径

可经呼吸道和消化道进入体内。

毒理学简介

大鼠经口LD50: 5 gm/kg; 吸入LCLo: 28800 ppm/15M。小鼠经口LD50: 4300 mg/kg; 吸入LC50: 12030 mg/m3/7H。兔经皮LD50: >20 gm/kg。

低毒。吸收后,有部分分解为无机溴盐,一部分经代谢产生一氧化碳。对中枢神经系统有抑制作用。对眼、皮肤和上呼吸道有轻度刺激作用。

IDLH: +2000 ppm [R8]

临床表现

对症处理。

美国HSDB引用文献：

*... THREE CASES OF ACUTE POISONING IN FIRE FIGHTERS USING CHLOROBROMOMETHANE AS A FIRE EXTINGUISHING AGENT /DESCRIBED/. THE CASES WERE CHARACTERIZED BY SEVERE HEADACHE, LOSS OF CONSCIOUSNESS AFTER EXPOSURE, GASTRIC UPSETS, LOSS IN WT & SLOW RECOVERY. EXPOSURES WERE BRIEF, BUT UNDOUBTEDLY AT VERY HIGH CONCN OF CHLOROBROMOMETHANE VAPOR. [R20]

*CORNEA WAS INJURED ... /WHEN/ FIRE EXTINGUISHER /CONTAINING CHLOROBROMOMETHANE & DICHLORODIFLUOROMETHANE/ WAS DISCHARGED CLOSE TO A PERSONS FACE. THE VICTIM FELT THE SPRAY OF LIQ & VAPOR HIT HIS FACE & EYES, CAUSING IMMEDIATE SEVERE BURNING SENSATION IN EYES. SOON THEREAFTER PARTIAL LOSS OF CORNEAL EPITHELIUM WAS OBSERVED, BUT DEEPER LAYERS OF CORNEA REMAINED CLEAR. CONJUNCTIVAE & LIDS WERE HYPEREMIC & EDEMATOUS. DISCOMFORT & PHOTOPHOBIA GRADUALLY SUBSIDED ... . [R21]

处理

对症治疗。

标准

车间空气卫生标准：

美国ACGIH TLV-TWA 1060 mg/m3 (200 ppm)

美国MSHA STANDARD-air: TWA 200 ppm (1050 mg/m3)

美国OSHA PEL(所有行业): 8H TWA 200 ppm (1050 mg/m3)

澳大利亚: TWA 200 ppm (1050 mg/m3), STEL 250 ppm (1300 mg/m3)

奥地利: TWA 200 ppm (1050 mg/m3)

丹麦: TWA 200 ppm (1050 mg/m3)

芬兰: TWA 200 ppm (1050 mg/m3), STEL 250 ppm (1315 mg/m3)

法国: TWA 200 ppm (1050 mg/m3)